Records 1-30 (of 49 Records) |
Query Trace: Kawasaki disease[original query] |
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Interaction Between Genetic Susceptibility and COVID-19 Pathogenesis in Pediatric Multisystem Inflammatory Disorders: The Role of Immune Responses. Chen Li-Na, et al. Viral immunology 2024 0 0. |
T Cell Receptor Sequences Amplified during Severe COVID-19 and Multisystem Inflammatory Syndrome in Children Mimic SARS-CoV-2, Its Bacterial Co-Infections and Host Autoantigens. Root-Bernstein Robert, et al. International journal of molecular sciences 2023 0 0. (2) |
Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children. Danyel Lee et al. Science (New York, N.Y.) 2022 12 (6632) eabo3627
Multisystem inflammatory syndrome in children (MIS-C) is a severe complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that affects one in 10,000 infected children. MIS-C is reminiscent of Kawasaki disease and its etiology remains unknown. Lee et al. performed whole-exome and whole-genome sequencing on a cohort of MIS-C patients and uncovered autosomal-recessive deficiencies of OAS1, OAS2, or RNASEL in around 1% of the cohort. These genes are components of a signaling pathway that suppresses inflammation in double-stranded RNA–stimulated mononuclear phagocytes.
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Host genetic susceptibility underlying SARS-CoV-2-associated Multisystem Inflammatory Syndrome in Brazilian Children. Santos-Rebouças Cíntia Barros, et al. Molecular medicine (Cambridge, Mass.) 2022 0 0. (1) 153 |
SARS-CoV-2 infection in the context of Kawasaki disease and multisystem inflammatory syndrome in children. Folga Barbara Anna, et al. Medical microbiology and immunology 2022 0 0. |
Single-cell sequencing of PBMC characterizes the altered transcriptomic landscape of classical monocytes in BNT162b2-induced myocarditis. Hwang Nahee, et al. Frontiers in immunology 2022 0 0. 979188 |
Clinical Subphenotypes of Multisystem Inflammatory Syndrome in Children: An EHR-based cohort study from the RECOVER program. Rao Suchitra, et al. medRxiv : the preprint server for health sciences 2022 0 0. |
Comparable bidirectional neutrophil immune dysregulation between Kawasaki disease and severe COVID-19. Chen Kuang-Den, et al. Frontiers in immunology 2022 0 0. 995886 |
Epigenetic profiling linked to multisystem inflammatory syndrome in children (MIS-C): A multicenter, retrospective study. Davalos Veronica, et al. EClinicalMedicine 2022 0 0. 101515 |
An Artificial Intelligence-guided signature reveals the shared host immune response in MIS-C and Kawasaki disease P Ghosh et al, Nature Comms, May 2022
We compare the two syndromes using a computational toolbox of two gene signatures that were developed in the context of SARS-CoV-2 infection, i.e., the viral pandemic (ViP) and severe-ViP signatures and a 13-transcript signature previously demonstrated to be diagnostic for KD, and validated our findings in whole blood RNA sequences, serum cytokines, and formalin fixed heart tissues. Results show that KD and MIS-C are on the same continuum of the host immune response as COVID-19. Both the pediatric syndromes converge upon an IL15/IL15RA-centric cytokine storm, suggestive of shared proximal pathways of immunopathogenesis
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Multicenter Validation of a Machine Learning Algorithm for Diagnosing Pediatric Patients with Multisystem Inflammatory Syndrome and Kawasaki Disease. Lam Jonathan Y, et al. medRxiv : the preprint server for health sciences 2022 0 0. |
Multicenter Validation of a Machine Learning Algorithm for Diagnosing Pediatric Patients with Multisystem Inflammatory Syndrome and Kawasaki Disease JY Lam et al, MEDRXIV, February 8,2022 |
X-Linked Lymphoproliferative Disease Mimicking Multisystem Inflammatory Syndrome in Children-A Case Report. Prader Seraina, et al. Frontiers in pediatrics 2021 0 0. 691024 |
SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease? Sancho-Shimizu Vanessa, et al. The Journal of experimental medicine 2021 0 0. (6) |
Impact of the COVID-19 pandemic on the frequency of the pediatric rheumatic diseases. Kaya Akca Ummusen, et al. Rheumatology international 2021 0 0. |
Host Genetics and Antiviral Immune Responses in Adult Patients With Multisystem Inflammatory Syndrome. Ronit Andreas, et al. Frontiers in immunology 2021 0 0. 718744 |
Multi-Inflammatory Syndrome in Children: A View into Immune Pathogenesis from a Laboratory Perspective. Bohn Mary Kathryn, et al. The journal of applied laboratory medicine 2021 0 0. |
Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children. Beckmann Noam D, et al. Nature communications 2021 0 0. (1) 4854 |
Innate immune response analysis in COVID-19 and kawasaki disease reveals MIS-C predictors. Yang Chin-An, et al. Journal of the Formosan Medical Association = Taiwan yi zhi 2021 0 0. |
An AI-guided invariant signature places MIS-C with Kawasaki disease in a continuum of host immune responses. Sahoo Debashis, et al. bioRxiv : the preprint server for biology 2021 0 0. |
Time of Onset of Selected Skin Lesions Associated with COVID-19: A Systematic Review. Gisondi Paolo, et al. Dermatology and therapy 2021 0 0. |
Phenotype, Susceptibility, Autoimmunity, and Immunotherapy Between Kawasaki Disease and Coronavirus Disease-19 Associated Multisystem Inflammatory Syndrome in Children. Chen Men-Ren, et al. Frontiers in immunology 2021 0 0. 632890 |
Clinical Characteristics of Paediatric Hyperinflammatory Syndrome in the Era of Corona Virus Disease 2019 (COVID-19). Basu Manjari, et al. Indian journal of clinical biochemistry : IJCB 2021 3 0. 1-12 |
Cytokine release syndrome in COVID-19: a major mechanism of morbidity and mortality. Que Yifan, et al. International reviews of immunology 2021 2 0. 1-14 |
Multisystem Inflammatory Syndrome of Children Related to SARS-CoV-2: A Novel Experience in Children with a Novel Virus. Bhattacharyya Parthasarathi, et al. Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine 2020 11 0. (11) 1010-1011 |
Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic in Paris, France: prospective observational study. Toubiana Julie, et al. BMJ (Clinical research ed.) 2020 0 0. m2094 |
Autoinflammatory and autoimmune conditions at the crossroad of COVID-19. Rodríguez Yhojan, et al. Journal of autoimmunity 2020 0 0. 102506 |
Multisystem Inflammatory Syndrome in Children Related to COVID-19: the First Case in Korea. Kim Haena, et al. Journal of Korean medical science 2020 0 0. (43) e391 |
Association between SARS-CoV-2 infection and Kawasaki-like multisystem inflammatory syndrome: a retrospective matched case-control study, Paris, France, April to May 2020. Toubiana Julie, et al. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2020 0 0. (48) |
Children are falling ill with perplexing inflammatory syndrome thought to be linked to Covid-19 Cha AE, Janes C. Washington Post, May 6, 2020. |
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